Grading of intrahepatic cholestasis of pregnancy / 中华妇产科杂志

ABSTRACT

Objective This study was to evaluate the grading of intrahepatic cholestasis of pregnancy (ICP) Methods All 278 ICP cases were collected in the First Affiliated Hospital of Chongqing Medical University between Jan 1999 and May 2003 They were graded into mild ICP and severe ICP based on liver function test Outcome of pregnancy and perinatal mortality were assessed Results One hundred and ninety two cases were diagnosed as mild ICP while 86 cases were as severe ICP There was significant difference in the average time of expectant therapy (10 3?4 8 vs 19 1?6 4 days) and gestational weeks (35 8?1 6 vs 37 7?1 9) between severe ICP and mild ICP groups ( P