Changes of VEGF protein and mRNA in the vulva of rabbits after ultrasound irradiation / 中华物理医学与康复杂志
Chinese Journal of Physical Medicine and Rehabilitation
;
(12)2003.
Artículo
en Chino
| WPRIM
| ID: wpr-682663
ABSTRACT
Objective To investigate ultrasound as a therapy for white lesions of the vulva.Methods Immunohistochemistry and hybridization in situ were used to study changes in VEGF protein and mRNA in the vulva skin of rabbits after ultrasound irradiation.Results After irradiation,VEGF protein and mRNA had increased markedly after 4 and 7 days,but their levels recovered by day 14.Conclusion Ultrasound irradiation causes local edema and hypoxia which enhance production of VEGF.VEGF promotes growth of local microvessels and increases the permeability of the endothelial cells of blood vessels.These changes improve nutrition of the mierovessels and nerve endings and ameliorate the microenvironment for tissue growth.One could speculate that ultrasound irradiation helps rehabilitation and regeneration of pathologic vulva skin.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Idioma:
Chino
Revista:
Chinese Journal of Physical Medicine and Rehabilitation
Año:
2003
Tipo del documento:
Artículo
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