SITE-DIRECTED MUTAGENESIS OF TSR1 GENE IN YEAST YARROWIA LIPOLYTICA / 微生物学通报

ABSTRACT

The TSR1(thermosensitive rescued)gene associated with the secretion of proteins of the yeast Yarrowia lipolytica was site-directed mutagenesis,restricted and spliced to obtain a series of deletion mutants.These mutants would be useful for studing the function of different domains of TSR1 gene in yeast Yarrowia lipolytica