Natural Anti-infectious Molecule:Bactericidal/permeability- increasing Protein / 中国生物工程杂志
China Biotechnology
; (12)2006.
Article
en Zh
| WPRIM
| ID: wpr-685039
Biblioteca responsable:
WPRO
ABSTRACT
Endotoxins are lipopolysaccharides ( LPS) , major component of out wall in Gram-negative bacteria. Often they are considered as "prime criminals" of triggering systemic inflaming reaction such as sepsis, bacteremia and so on. It was found in recent years that bactericidal/permeability-increasing protein, a 55kDa member of lipid-related protein family, was a kind of natural molecule of anti-infection and it has special endotoxin-neutralising activity and antibacterial activity. Comprehensive phase II/III clinical trials demonstrated the feasibility and safety of recombinant BPI. So pharmaceutical corporations are attracted to try to apply it to therapy.
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Índice:
WPRIM
Idioma:
Zh
Revista:
China Biotechnology
Año:
2006
Tipo del documento:
Article