A weak D type 59 case identified in the Chinese Han population / 中华医学遗传学杂志
Chinese Journal of Medical Genetics
;
(6): 261-264, 2018.
Artículo
en Chino
| WPRIM
| ID: wpr-687964
ABSTRACT
<p><b>OBJECTIVE</b>To study a case with weak D59 phenotype identified among ethnic Han Chinese population.</p><p><b>METHODS</b>Routine serological tests were used to analyze the reaction patterns, and the RhD epitopes were verified with 12 monoclonal antibodies. Sequence-specific primer PCR was applied for typing the weak RhD and RhD zygosity in the proband and his family members.</p><p><b>RESULTS</b>A c.1148T>C variant was identified in the proband, for which serological test indicated a weak D phenotype. RHD zygosity testing confirmed that the proband had a RHD+ /RHD- genotype.</p><p><b>CONCLUSION</b>A weak D59 phenotype was firstly identified in a Chinese individual.</p>
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Fenotipo
/
Sistema del Grupo Sanguíneo Rh-Hr
/
China
/
Pueblo Asiatico
/
Etnología
/
Genética
Tipo de estudio:
Estudio pronóstico
Límite:
Humanos
/
Masculino
País/Región como asunto:
Asia
Idioma:
Chino
Revista:
Chinese Journal of Medical Genetics
Año:
2018
Tipo del documento:
Artículo
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