Binocular lateral rectus recession versus monocular recess-resect procedure for basic intermittent exotropia:a Meta analysis of randomized controlled trials / 国际眼科杂志(Guoji Yanke Zazhi)

ABSTRACT

@#AIM:To compare the curative effect between monocular lateral rectus recession(BLR)and Binocular recession resection(R & R)for basic intermittent exotropia.<p>METHODS:A literature review using the MEDLINE, EMBASE, The Cochrane Library, Web of Science, Clinical Trial, CBM, Wanfang Databases and paper collections of conferences was performed. Randomized controlled trials comparing the effects of BLR and R & R for basic intermittent exotropia with a duration of follow-up at least half a year were eligible for inclusion. The methodologic quality of included studies was evaluated independently by 2 authors. Statistical analysis was performed by using the STATA 14 software(StataCorp Texas USA).<p>RESULTS:Five prospective random controlled clinical trials involving 529 patients were included. Compared with R & R procedure,the BLR procedure group showed lower successful rate(<i>RR</i>0.85; 95% <i>CI</i>0.72-0.99; <i>P</i>=0.043)and postoperative undercorrection(<i>RR</i>3.975; 95% <i>CI</i>2.097-7.537; <i>P</i><0.01). The <i>P</i> value of long-term postoperative corrected rate in Meta analysis was decreased near to 0.05 when the included references increased. There was no significant difference in overcorrection rate between the BLR and R & R procedures(<i>RR</i>0.336; 95% <i>CI</i>0.049-2.294; <i>P</i>=0.266).<p>CONCLUSION:Current evidences suggested that BLR procedure is related to lower successful and higher undercorrection rates for basic intermittent exotropia compared to conventional R & R procedure.