Insomnia in Relation to Suicide and Serotonin in Patients with Major Depressive Disorder / 수면정신생리
Sleep Medicine and Psychophysiology
; : 29-32, 2014.
Article
en Ko
| WPRIM
| ID: wpr-69002
Biblioteca responsable:
WPRO
ABSTRACT
OBJECTIVES: The aim of current study is to evaluate the relationship between sleep, suicide and serotonin using some scales and loudness dependence of auditory evoked potentials (LDAEP). METHODS: Total 65 patients who met the criteria for major depressive disorder were enrolled in current study. The patients were divided into two subgroups according to their insomnia and a history of suicide attempts. The auditory event-related potentials were measured to evaluate LDAEP before beginning antidepressants. RESULTS: The scores of total Beck Depression Inventory (BDI) and BDI item 9 (suicide) were higher in insomnia subgroup than non-insomnia subgroup (respectively, p=0.0033 and p=0.03). However, LDAEP did not differ each other. The subgroup with a history of suicide attempts had a higher score of BDI item 9 than the subgroup without a history of suicide attempts (p=0.00012). There was a tendency for the LDAEP to be higher in the subgroup with a history of suicide attempts (1.39+/-0.94 microV) than the subgroup without a history of suicide attempts (1.05+/-0.75 microV), although the difference was not statistically significant (p=0.078). CONCLUSION: Suicidality was related to insomnia. In addition, there was a tendency for serotonin activity to be lower in the subgroup with a history of suicide attempts. In future, more studies are needed.
Palabras clave
Texto completo:
1
Índice:
WPRIM
Asunto principal:
Suicidio
/
Pesos y Medidas
/
Serotonina
/
Depresión
/
Trastorno Depresivo Mayor
/
Potenciales Evocados
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Potenciales Evocados Auditivos
/
Trastornos del Inicio y del Mantenimiento del Sueño
/
Antidepresivos
Límite:
Humans
Idioma:
Ko
Revista:
Sleep Medicine and Psychophysiology
Año:
2014
Tipo del documento:
Article