IgG4-Related Tubulointerstitial Nephritis Accompanied by Henoch-Schonlein Purpura / 대한내과학회지
Korean Journal of Medicine
; : 96-100, 2014.
Article
en Ko
| WPRIM
| ID: wpr-69085
Biblioteca responsable:
WPRO
ABSTRACT
Tubulointerstitial nephritis is one of the common manifestations of immunoglobulin G (IgG)4-related disease; however, among all cases of tubulointerstitial nephritis undergoing renal biopsies, IgG4-related tubulointerstitial nephritis seems to be relatively rare because of its trivial urinary findings. A previously healthy 54-year-old man was referred to our clinic with a 4-week history of lower leg purpura and renal dysfunction. A kidney biopsy was planned because of bilateral renomegaly, by imaging studies, and elevated serum creatinine levels. Pathological findings in the kidney showed prominent infiltration of IgG4-postive plasma cells in the tubulointerstitium, but not the glumeruli. A skin biopsy revealed leukocytoclastic vasculitis, accompanied by deposition of IgA and C3 in the vascular wall, indicating Henoch-Schonlein purpura (HSP). Although cases of combined IgG4-related disease and microvasculitis, including HSP, are extremely rare, the possibility of an association between two diseases deserves attention.
Palabras clave
Texto completo:
1
Índice:
WPRIM
Asunto principal:
Células Plasmáticas
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Púrpura
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Vasculitis por IgA
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Piel
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Vasculitis
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Biopsia
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Inmunoglobulina A
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Inmunoglobulina G
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Creatinina
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Riñón
Límite:
Humans
Idioma:
Ko
Revista:
Korean Journal of Medicine
Año:
2014
Tipo del documento:
Article