Clinical significance of neutrophil gelatinase-associated lipocalin in pediatric renal diseases / 国际儿科学杂志

ABSTRACT

Neutrophil gelatinase-associated lipocalin,a small molecular lipocalin secreted by neutro phils,has a close relationship with inflammation,immune response,tumor,kidney diseases,etc.Recent studies have found that NGAL has a protective effect on kidney,and could be used as an effective indicator for early monitoring of kidney diseases.The review mainly summarizes the mechanisms,physiological functions and clinical applications of pediatric renal diseases.