Protective effects of inhaled anesthetics on hypoxic-ischemic damage in neonates / 国际儿科学杂志

ABSTRACT

Neonatal hypoxic-ischemic encephalopathy (HIE) is a leading cause of infant morbidity and mortality,often causing irreversible brain damage,and eventually leading to neurodevelopmental and cognitive dysfunction.Previous studies have shown that some commonly used inhaled anesthetics has certain neuroprotective effects on hypoxic-ischemic brain damage(HIBD),but its mode of action and the mechanisms are not clear.In this review,the protective effect of inhaled anesthetics on HIBD in neonates and its related mechanisms are described.