Immunosuppression of sepsis / 国际儿科学杂志

ABSTRACT

Sepsis is an infectious disease that affects immune function by various inflammatory factors and is the main cause of death in ICU patients. As a syndrome caused by uncontrollable inflammation,sepsis not only contains a large number of continuous inflammatory reactions,but also has a long-term immunosuppressive state,which increases the probability of secondary nosocomial infection in patients with sepsis. The immune sta-tus of patients with sepsis will change with the progression of the disease,and different biomarkers help to ex-plain the immune stage of patients. Immune-enhancing therapy is expected to reduce the mortality rate of sepsis patients in the stage of immunoparalysis.