Progress of therapy for pediatric dliated cardiomyopathy / 国际儿科学杂志

ABSTRACT

Pediatric dilated cardiomyopathy( PDCM) is not only associated with infection,metabolism and other factors, but also a congenital cardiomyopathy. PDCM echocardiography ( ultrasonic cardiogram ) showed a severe enlargement of the left ventricle or double ventricle,with decreased left ventricle ejection con-traction. Clinical onset of disease concealment,often manifested as refractory heart failure,arrhythmia and sudden death( heart function often reached III～IV level) . The prognosis of the disease is poor,and mortality and mor-bidity are high,which may be the main cause of heart transplantation in children. Over the past three decades, treatment of left ventricular dysfunction has been the focus of research on adult cardiomyopathy,and treatment of PDCM has mostly extended from the treatment of dilated cardiomyopathy in adults. This article will provide the guidance of adult patients with cardiac dilation therapy,and is combined with recent research at home and abroad to illustrate the latest research and experience of PDCM treatment,and to explore the progress of PDCM treat-ment in recent years.