Analysis of the changes of blood immune indicators in 291 cases of voluntary blood donors / 国际检验医学杂志

ABSTRACT

Objective To investigate the changes of lymphocyte subsets of 291 blood donors after dona-tion.Methods 291 cases of voluntary blood donors were enrolled in the study from January 2016 to December 2016.Before and 30 d after blood donation,cellular immune function and humoral immune function.The cellu-lar immune function and humoral immune function of 30 d before and after blood donation were compared,the changes of cellular immune function and humoral immune function before and after donation of 30 d between different genders.Results 30 d after blood donation,CD3+,CD4+lymphocytes and CD4+/CD8+were higher than those before blood donation(P<0.05).There was no significant difference in the levels of IgA,IgM and IgG before and after blood donation(P> 0.05).30 d after blood donation,CD3+,CD4+lymphocytes,and CD4+/CD8+were all higher than those before blood donation in both males and females(P<0.05);CD3+, CD4+lymphocytes,and CD4+/CD8+were detected before and after blood donation,between different genders there was no significant difference(P>0.05).There was no significant difference between males and females in IgA,IgM and IgG before and after blood donation(P>0.05).Conclusion There was no significant change in the humoral immune function in 291 cases of voluntary blood donors,but the proportion of T cell subsets increased.