Relationship between thrombosis and platelet aggregation function in patients with acute cerebral infarction / 国际检验医学杂志

ABSTRACT

Objective To study the relationship between thrombocytopenia and platelet aggregation func-tion in patients with acute cerebral infarction.Methods Selected 100 patients with acute cerebral infarction re-ceived from our hospital from May 2016 to May 2017 as observation group,and 100 healthy patients as control group.were tested for the blood elasticity,platelet aggregation function and routine coagulation function test. Correlation between Preason and platelet aggregation function and coagulation function in patients with acute cerebral infarction was analyzed by correlation analysis.Results The observation group of patients with R,K levels(6.0 ± 1.8)min,(1.1 ± 0.3)min,were significantly lower than in the control group(6.8 ± 2.2)min and(2.2 ± 0.5)min(P<0.05).The MA、platelet aggregation rate in the observation group was(69.4 ± 5.0) mm、(71.9 ± 11.2)%,significantly higher than the control group(60.1 ± 4.6)mm、(55.7 ± 9.2)%(P<0.05).The levels of DD and FIB in the observation group were(0.4 ± 0.2)mg/L,(4.5 ± 0.7)g/L,both sig-nificantly higher than that in the control group(0.2 ± 0.01)mg/L,(2.7 ± 0.8)g/L,and the differences were statistically significant(all P<0.05).The Preason correlation analysis availableR,K and platelet aggregation in patients with acute cerebral infarction rate were negatively related,DD and FIB,MA and rate of platelet ag-gregation in patients with acute cerebral infarction,DD and FIB were positively correlated relationship(all P<0.05).Conclusion Thrombosis elastic parameters and platelet aggregation function in patients with acute cer-ebral infarction and obvious correlation,blood coagulation function in clinical work by thrombus elastic graph examination is helpful for the evaluation of the patient condition,so as to effectively guide the clinical treat-ment.