The application of thyroid function tests in elderly patients with cardiovascular disease / 国际检验医学杂志

ABSTRACT

Objective To investigate the clinical application value of thyroid examination for elderly pa-tients with cardiovascular disease.Methods 845 cases from 60 to 89 years old ,who were initially diagnosed as cardiovascular disease in a hospital in Chongqing from December 2013 to November 2014 ,were selected as the case group.Another 200 healthy persons in the same age group who underwent the healthy assessment in the physical examination center of the hospital during the same period were selected as the control group.The lev-els of thyroid hormone were detected in two groups.Results The abnormal type of thyroid function in the case group had a statistically significant difference in different age distribution (P＜0.05).The detection rate of thyroid dysfunction was significantly higher in the case group than that in the control group ,and the differ-ence was statistically significant (P＜0.05).The differences of thyrotropin stimulating hormone (TSH) ,free triiodothyronine(FT3) and free thyroxine(FT4) concentrations between the control group and the case group were statistically significant (P＜0.01).In comparison with the results in the control group ,the concentration of TSH in patients with coronary heart disease and atrial fibrillation increased significantly ,the TSH concen-tration of patients with arrhythmia decreased significantly ,the concentrations of FT3 and FT4 in patients with hypertension and coronary heart disease increased significantly ,the FT3 concentration in patients with ar-rhythmia significantly increased ,and the concentrations of FT 3 and FT4 in patients with atrial fibrillation sig-nificantly decreased ,and the differences were statistically significant (P＜0.01).Conclusion The thyroid dys-function has a high detection rate in elderly patients with cardiovascular disease ,and all kinds of abnormalities may have an effect on the cardiovascular system.Thus ,active control of the abnormal thyroid hormone value can significantly improve the patients' cardiac function.Therefore ,for elderly patients with cardiovascular dis-ease ,routine screening of thyroid function is conducive to the diagnosis and treatment of their cardiovascular diseases.