Radiotherapy for limited-stage small cell lung cancer / 国际肿瘤学杂志

ABSTRACT

Small cell lung cancer (SCLC) presents the characteristics of high malignant degree and distant metastasis.About 25％ ～ 30％ of the patients with SCLC are confirmed to be limited stage (LS)-SCLC at first visit.Early chest radiotherapy should be a better option for the timing of radiotherapy for LS-SCLC,EP scheme (etoposide + cisplatin) chemotherapy combined with radiotherapy is acceptable for the sequence of radiotherapy and chemotherapy.CT,MRI,PET imaging visible tumors should be considered as the radiotherapy targets.Radiation dose and segmentation methods should be improved total dose of radiation or altered fractionated radiotherapy.Prophylactic cranial irradiation can improve the 3-year survive and reduce brain metastasis rate of patients with LS-SCLC.