Immunotherapy of targeting at tumor stem cells / 基础医学与临床

ABSTRACT

Tumor stem cells (TSCs), because of its close related to occurrence, development, metastasis, recurrence and drug resistance of tumor, are considered by research commnity as a root cell bank of the tumor. In other words, The key way to cure tumor may be to eradicate TSCs. The traditional surgery, chemotherapy and radiothera-py not only have few effect in killing TSCs, but result in recurrence and metastasis easily. However, TSCs can definitely killed by the immunotherapy targeting TSCs, for instance, targeting the surface antigens of TSCs', T cells tar-getting the TSCs, differentiation therapy and so on.