Consistency Analysis of Urine Albumin Results by Urinary Dry Chemical Analysis,Scatter Turbidimetry,Enzymatic Assays and Urine Creatinine and Albumin-to-Creatinine Ratio / 现代检验医学杂志

ABSTRACT

Objective To analysis of consistency of results in evaluating urine dry chemical method and nephelometry in the detection of urine albumin(UAlb) and urine dry chemical method and enzymatic method in the detection of urinary creatinine (Cr) and albumin-to-creatinine ratio(ACR).Methods In 157 urine samples collected firstly in the morning,urine microalbumin was determined by the urine dry chemistry method and nephelometry,and urine creatinine was determined by the urine dry chemistry method and the enzyme method respectively.The kappa was applied to evaluating the consistency.Results The results of UAlb showed that the kappa was 0.837 9 (95％CI0.718 1～0.957 7),the results of urine creatinine showed that the kappa was 0.769 7 (95％CI0.665 2～0.874 2),and the results of albumin-to creatinine ratio showed that the kappa was 0.756 6 (95％CI0.628 6～0.884 6).Conclusion The results of urine Alb,urinary creatininc and ACR by urine dry chemistry method and urine albumin by nephelometry,and urine Cr by enzymatic method and ACR had high consistency.Urine dry chemical method can be used for screening of early renal disease and for screening in CKD grading,screening for early screening or for long-term maintenance.