Study progress of role of Toll-like receptor 9 in pathogenesis of viral myocarditis / 中华实用儿科临床杂志
Chinese Journal of Applied Clinical Pediatrics
;
(24): 78-80, 2018.
Artículo
en Chino
| WPRIM
| ID: wpr-696333
ABSTRACT
Toll - like receptors represents the first line of defense against foreign pathogens and play an essen-tial role in the innate immune response. Toll - like receptor 9(TLR9)is a major receptor mediating CpG DNA signal transduction,which can not only resist inflammation but also induce inflammatory damage. Studies show that the activa-tion of TLR9 which mediated by endogenous nucleic acid released during viral myocarditis (VMC)can cause the heart damage and be involved in the process of VMC. Further study on the role of TLR9 signal in VMC will provide a theoreti-cal foundation for further revealing the pathogenesis of VMC and seeking effective treatment.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Tipo de estudio:
Estudio de etiología
Idioma:
Chino
Revista:
Chinese Journal of Applied Clinical Pediatrics
Año:
2018
Tipo del documento:
Artículo
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