Characteristics of bone marrow examination in systemic lupus erythematosus patients with blood system damage / 实用医学杂志

ABSTRACT

Objective To investigate the characteristics of bone marrow examination in systemic lupus erythematosus (SLE) patients with blood system damage.Methods The data of 150 SLE patients with bone marrow puncture were analyzed retrospectively.Results Of the 150 patients,68 patients had abnormalities in bone marrow examination.Common bone marrow abnormalities were low proliferative bone marrow (26 cases,38.2％),hemophagocytic (17 cases,25％),pure red blood cells aplastic anemia (6 cases,8.8％),aplastic anemia (12 cases,17.6％) and decreased megakaryocyte count (7 cases,10.4％).10 cases of severe and severe anemia (90.9％ of patients with severe and severe anemia) and 21 patients with severe thrombocytopenia (67.7％ of patients with severe thrombocytopenia) had abnormal bone marrow examination.Conclusions It is not uncommon for SLE patients to have abnormal bone marrow examination.When the peripheral blood test is found to be severe anemia or severe thrombocytopenia,bone marrow aspiration and bone marrow biopsy are needed.