Analysis of off-label use of anti-infective drugs in children / 中国小儿急救医学

ABSTRACT

Off-label use or unlicensed use of anti-infective drugs is most commonly in children both in the outpatient and inpatient settings. Off-label anti-infective drug use is due to dosage,frequency,patient age,indication,route of administration,or contraindications. Off-label use of drugs does not necessarily mean unsafe use. Off-label drug use should be based on high-quality evidence;use within the context of a formal research proposal and exceptional use.