Cerebrovascular complications in autosomal dominant polycystic kidney disease(ADPKD) / 대한내과학회지
Korean Journal of Medicine
;
: 75-82, 2000.
Artículo
en Coreano
| WPRIM
| ID: wpr-70055
ABSTRACT
BACKGROUND:
ADPKD is one of the most common hereditary renal disease in adult and is a systemic disorder with a variety of cardiovascular manifestations. To elucidate the clinical characteristics of cerebrovascular complications in Korean ADPKD patients, we reviewed the medical records of ADPKD patients who was registered in ADPKD clinic of Seoul National University Hospital.METHODS:
A total of 18 adult patients were included and their sex ratio was 810. The median age of ADPKD diagnosis was 45.5 year (range 19-85), and age at cerebrovascular accident(CVA) was 52 years(22-82). The median duration from hypertension to CVA was 8 years(0-30).RESULTS:
There were 5 cases of infarction, 4 cases of intracerebral hemorrhage, 4 cases of subarachnoid hemorrhage, and 4 cases of transient ischemic attack. Other clinical parameters of ADPKD were not different from patients who were not complicated with CVA. Intracranial aneurysms were detected in 6 patients and their median age at diagnosis was 47.5 years(33-66). Four cases were manifested as subarachnoid hemorrhage. Five cases were diagnosed through TFCA, and two of them were revealed as multiple aneurysms. Five cases received surgical treatment and five of six cases improved without any neurologic sequeale. MR angiography(MRA) were taken in 16 asymptomatic patients, and multiple aneurysms were newly detected in one of them.CONCLUSION:
Cerebrovascular complications in Korean ADPKD patients were not significantly different from western patients. Intracranial aneurysms must be included in differential diagnosis in ADPKD patients who manifest an acute neurologic symptoms, and high-risk group need to be screened selectively with MRA.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Razón de Masculinidad
/
Hemorragia Subaracnoidea
/
Aneurisma Intracraneal
/
Hemorragia Cerebral
/
Ataque Isquémico Transitorio
/
Registros Médicos
/
Riñón Poliquístico Autosómico Dominante
/
Diagnóstico
/
Diagnóstico Diferencial
/
Seúl
Tipo de estudio:
Estudio diagnóstico
Límite:
Adulto
/
Humanos
País/Región como asunto:
Asia
Idioma:
Coreano
Revista:
Korean Journal of Medicine
Año:
2000
Tipo del documento:
Artículo
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