Progress in betatrophin research / 医学研究生学报

ABSTRACT

Betatrophin is a new kind of secretory glycoprotein,which belongs to the angiopoietin like protein family.It ex-pressed in liver and adipose tissue,and their expression level are affected by age,gender and thyroid hormone. The active mechanism of Betatrophin mechanism is still unclear. It plays an important role in the islet beta cell proliferation and in the lipid metabolism. In this paper,we mainly focus on the structure of betatrophin and the related research on blood glucose and lipid,metabolic syndrome and nonalcoholic fatty liver in recent years.