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Clinical characteristics of 72 patients with brucellosis / 中华地方病学杂志
Chinese Journal of Endemiology ; (12): 822-825, 2018.
Artículo en Chino | WPRIM | ID: wpr-701437
ABSTRACT
Objective To analyze and review clinical characteristics of brucellosis and improve awareness of brucellosis and level of diagnosis.Methods Totally 72 in-patients treated for brucellosis from March 2012 to June 2015 in Affiliated Hospital of Jining Medical University were retrospectively analyzed for epidemiology,clinical feature,laboratory data,treatment and prognosis.Results A total of 72 cases were confirmed and included.Thirty seven patients (51.39%) had definitely contact history with raw meat or progeny and 3 (4.17%) with brucellosis patients.The common clinical presentations included persistent fever (100.00 %,72/72),followed by headache (87.50%,63/72),chills (48.61%,35/72),muscle-joint pain (47.22%,34/72) and cough (43.06%,31/72).The laboratory test showed there were 14 patients (19.44%,14/72) with decreased leukopenia,49 patients (68.06%,49/72) with elevated C-reactive protein and 46 patients (63.89%,46/72) with elevated procalcitonin.Abnormal liver function showed elevated alanine aminotransferase (69.44%,50/72),aspartate aminotransferase (66.67%,48/72) and alkaline phosphatase (61.11%,44/72) with proportions.The mainly abnormal imaging features showed hepatomegaly,splenomegaly,lymphadenopathy,pulmonary infiltrating and nodules.Sixty-five patients (90.28%) had positive blood culture and 13 cases (18.06%) had positive marrow culture.Seventy-two patients were cured after active medical treatment and no recurrence after 1 year of follow-up.Conclusions Brucellosis is a invasive infectious disease with many systemic involvements,whose clinical symptoms are not typical.For those patients with long-term fever of unknown origin and poor effect anti-infection treatment,especially complicated with multi-system damage hepatomegaly,splenomegaly,lymphadenopathy,brucellosis should be suspected and be treated early.

Texto completo: Disponible Índice: WPRIM (Pacífico Occidental) Tipo de estudio: Estudio pronóstico Idioma: Chino Revista: Chinese Journal of Endemiology Año: 2018 Tipo del documento: Artículo

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Texto completo: Disponible Índice: WPRIM (Pacífico Occidental) Tipo de estudio: Estudio pronóstico Idioma: Chino Revista: Chinese Journal of Endemiology Año: 2018 Tipo del documento: Artículo