Clinical effect of concurrent radiotherapy and chemotherapy in the treatment of 60 patients with advanced cervical cancer / 中国基层医药

ABSTRACT

Objective To explore the clinical effect of concurrent radiotherapy and chemotherapy in the treatment of advanced cervical cancer.Methods From January 2010 to January 2011,sixty patients with cervical cancer in Taizhou Cancer Hospital were randomly divided into two groups ,with 30 cases in each group.The control group was given radiotherapy alone ,the observation group was given concurrent radiotherapy and chemotherapy .The adverse reaction,curative effect,long -term effect of 5 -year follow -up were compared between the two groups. Results The total effective rate of the observation group was 93.33%,which was significantly higher than 73.33%of the control group,the difference was statistically significant (χ2＝14.397,P＜0.05).The 5-year survival rate of the observation group was 76.67%,which was significantly higher than 53.33% of the control group,the difference was statistically significant ( χ2＝11.922,P ＜0.05).The local recurrence rate and distant metastasis rate of the observation group were 16.67%,13.33%,respectively,which were significantly lower than those of the control group , the differences were statistically significant (χ2＝7.401,5.115,all P＜0.05).The incidence rate of adverse reaction of the control group was 13.33%,which of in the observation group was 23.33%,the difference was not statistically significant(χ2＝3.340,P ＞0.05).Conclusion The efficacy of concurrent radiotherapy and chemotherapy for patients with advanced cervical cancer is better ,and the survival rate of patients with advanced cervical cancer is better.