Profile of serum lipoprotein in patients with subclinical hypothyroidism
Journal of the Korean Academy of Family Medicine
;
: 376-381, 2000.
Artículo
en Coreano
| WPRIM
| ID: wpr-7022
ABSTRACT
BACKGROUND:
Overt hypothyroidism is a well-known cause of secondary hyperlipidemia and atherosclerosis. However, there have been some dissenting report of abnormalities and in serum lipid concentration in patients with subclinical hypothyroidism. We have attempted to analyze serum lipid concentrations to investigate whether they are increased in patients with subclinical hypothyroidism and to see if there is a correlation between serum LDL-C and TSH concentrations.METHODS:
Serum lipid profiles(total cholesterol, triglycerides, LDL-C, HDL-C) of patients with subclinical hypothyroidism (M/F=7/119) compared with age, sex and body mass index matched control subjects(M/F=14/239) from Jan. 1 . 1996. to Dec. 30. 1997.RESULTS:
There were no significant differences of serum total cholesterol, LDL cholesterol, TG, and HDL concentrations in 126 patients with subclinical hypothyroidism and 253 control subjects(178.47+/-35.76mg/dL vs. 173.05+/-35.93mg/dL ; 113.33+/-52.89mg/dL vs 117.64+/-68.70mg/dL ; 112.89+/-33.26mg.dL vs 109.65+/-29.02mg/dL ; 48.60+/-11.34mg/dL vs 46.51+/-11.73mg/dL). There was no correlation between LDL cholesterol and TSH concentrations in subclinical hypothyroidism(r=0.29, p<0.05).CONCLUSION:
Serum lipid concentration (total cholesterol, LDL cholesterol, and TG, HDL) was not increased in patients with subclinical hypothyroidism. There was no correltion between serum LDL and TSH levels in patients with subclinical hypothyroidism.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Triglicéridos
/
Índice de Masa Corporal
/
Colesterol
/
Disentimientos y Disputas
/
Aterosclerosis
/
Hiperlipidemias
/
Hipotiroidismo
/
Lipoproteínas
/
LDL-Colesterol
Límite:
Humanos
Idioma:
Coreano
Revista:
Journal of the Korean Academy of Family Medicine
Año:
2000
Tipo del documento:
Artículo
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