Is Antipsychotic Intake a Risk Factor for the Restless Legs Syndrome?
Journal of the Korean Neurological Association
;
: 49-53, 2009.
Artículo
en Coreano
| WPRIM
| ID: wpr-70320
ABSTRACT
BACKGROUND:
Restless-legs syndrome (RLS) is known to be caused by dopaminergic hypofunction in the brain. We investigated whether antipsychotics that act as antidopaminergics increase the risk of RLS.METHODS:
We prospectively recruited 72 schizophrenic patients who had been medicated with antipsychotic drugs in a psychiatry clinic. We evaluated RLS diagnostic criteria and basic sleep habits using the Epworth Sleepiness Scale and Pittsburgh Sleep Quality Index by face-to-face interviews using a structured questionnaire. We also applied the Unified Parkinson's Disease Rating Scale to evaluate extrapyramidal symptoms.RESULTS:
Three of the 72 patients (4.2%) met RLS criteria, which is similar to the previously reported RLS incidence among the general population in Korea.CONCLUSIONS:
There is no evidence that antipsychotics increase the risk of RLS. We believe that the mild antidopaminergic effect of antipsychotics does not overwhelm their prominent antipsychotic effect.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Enfermedad de Parkinson
/
Síndrome de las Piernas Inquietas
/
Esquizofrenia
/
Antipsicóticos
/
Encéfalo
/
Incidencia
/
Estudios Prospectivos
/
Encuestas y Cuestionarios
/
Factores de Riesgo
Tipo de estudio:
Estudio de etiología
/
Estudio de incidencia
/
Estudio observacional
/
Estudio pronóstico
/
Investigación cualitativa
/
Factores de riesgo
Límite:
Humanos
Idioma:
Coreano
Revista:
Journal of the Korean Neurological Association
Año:
2009
Tipo del documento:
Artículo
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