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Phagocytic function of microglia and underlying regulatory mechanism in neurodevelopment and neurodegenerative diseases / 中国比较医学杂志
Chinese Journal of Comparative Medicine ; (6): 120-126,102, 2018.
Artículo en Chino | WPRIM | ID: wpr-703330
ABSTRACT
Microglia, a type of neuroglia, has a variety of functions such as phagocytosis, clearance, antigen presentation,promotion of repairment of injury and secretion of extracellular signaling molecules,in which phagocytosis of microglia plays a crucial role in maintaining brain tissue,remodeling synapses,clearance of several aberrant proteins such as amyloid β in neurodegenerative diseases, and in neurodevelopment. This review briefly summarizes the phagocytic function of microglia with underlying regulatory mechanism in neurodevelopment and neurodegenerative diseases,aiming to provide a new thought for the therapy of neurodegenerative diseases.

Texto completo: Disponible Índice: WPRIM (Pacífico Occidental) Idioma: Chino Revista: Chinese Journal of Comparative Medicine Año: 2018 Tipo del documento: Artículo

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Texto completo: Disponible Índice: WPRIM (Pacífico Occidental) Idioma: Chino Revista: Chinese Journal of Comparative Medicine Año: 2018 Tipo del documento: Artículo