Predict Value of Controlling Nutritional Score on Mortality of Patients With Acute Myocardial Infarction After Percutaneous Coronary Intervention / 中国循环杂志

ABSTRACT

Objectives: To evaluate the impact of nutritional states on mortality of acute myocardial infarction (AMI) patients by the controlling nutritional (CONUT) score. Methods: We performed a monocentric retrospective cohort study among AMI patients after percutaneous coronary intervention(PCI) and the median follow-up was 36(33, 36 interquartile range) months. The endpoint was all cause of death. Information was obtained by medical records, clinical visit and telephone calls.Patients were divided into three groupsnormal(CONUT=0~1, n=304),mild malnutrition (CONUT=2~4, n=476) and moderate-severe malnutrition (CONUT=5~12, n=58) groups.The differences on mortality among groups were compared by Kaplan-Meier survival analysis. Results: 51 patients out of 838 patients died during follow up, 63.7% patients were in the malnutrition state according to the CONUT score.The mortality was 2.6%, 6.3%, and 22.4% in normal, mild malnutrition and moderate-severe malnutrition groups, respectively.The mortality was significantly higher in mild and moderate-severe groups than in normal group (P=0.021, P<0.001, respectively). The Cox proportional hazard analyses revealed that the risk of all cause of death of both mild and moderate-severe groups were significantly higher than in normal group in full-adjusted model (Mild HR[95%CI]3.473[1.507-8.003] , P=0.003; moderate-severe HR[95%CI] 10.775[3.958-29.334] , P<0.001). Conclusions: Malnutrition is a common phenomenon in AMI patients treated with PCI and relates to increased risk of all-cause mortality. CONUT score could be used to predict the risk of all-cause mortality in AMI patients undergoing PCI.