Correlation between Ischemia-modified Albumin Levels and Coronary Artery Lesions in Patients with Acute Coronary Syndrome / 中国医科大学学报

ABSTRACT

Objective To evaluate the correlation between ischemia-modified albumin (IMA) levels and severity of coronary artery lesions in patients with acute coronary syndrome (ACS).Methods This study included 51 in-hospital patients diagnosed as having ACS.All patients had undergone coronary angiography and received the standard treatment for coronary heart disease.Meanwhile,we included 10 healthy volunteers as the control group.Coronary angiography reports were collected,Gensini scores were calculated,and serum IMA levels were measured.Results The IMA levels of patients with ACS were higher than those of the controls (P ＜ 0.05).However,when divided by the degree of coronary artery stenosis,number of vessel lesions,and Gensini scores,the IMA levels showed no significant difference between the groups.The IMA levels were not related with the Gensini scores.The moderate group had a low ratio of TIMI flow grade 3.Conclusion Patients with ACS had higher IMA levels.We found no correlation between IMA level and coronary artery lesions.IMA level may not accurately reflect the severity of coronary artery lesions.Increased IMA level may indicate the unstable status of ischemia.