Four-dimensional Quantitative Analysis of Right Ventricular Systolic Function in Hypertension / 中国医学影像学杂志

ABSTRACT

Purpose To explore the change of right ventricular systolic function in hypertensive patients with or without left ventricular hypertrophy at different stages using four-dimensional right ventricular quantitative analysis (4D-RV-Volume). Materials and Methods Ninety-six cases of clinically diagnosed hypertension were divided into left ventricular mass index (LVMI) normal group (49 cases) and LVMI increased group (47 cases) according to LVMI, and 53 cases were chosen from healthy control group for echocardiography to check parameters of right ventricular systolic function such as right ventricular ejection fraction (RVEF), end-diastolic volume (RVEDV), end-systolic volume (RVESV), longitudinal strain rate of free wall (RVFLS), longitudinal strain rate of ventricular septum (RVSLS), fractional area change (RVFAC), tricuspid annular plane systolic excursion (TAPSE), and the difference among groups were compared. Results Compared with control group, RVEF, RVFLS, and RFAFC in all hypertension groups decreased, the difference of which was statistically significant (P<0.05); compared with LVMI normal group, RVEF, RVFLS, TAPSE and RFAFC in LVMI increased group further decreased, the difference of which was statistically significance (P<0.05); RVEF was positively correlated with RFAFC (r=0.721, P<0.01); when RVEF was 46.5% (AUC=0.859, P<0.001), the diagnostic value was the highest with a sensitivity of 68.0%, and specificity of 85.7%. Conclusion Right ventricular systolic dysfunction exists in different periods of hypertension, and 4D-RV-Volume provides a new approach for early evaluation of right ventricular dysfunction in hypertensive patients.