The mechanism of tumor immune escape and research progress in esophageal cancer / 中国肿瘤临床

ABSTRACT

Escape from anti-tumor immunity is critical for tumor survival and progression.Tumor cells can suppress the anti-tumor im-mune response via recruitment of various immune cell populations or expression of inhibitory molecular factors.Esophageal cancer is a deadly disease,ranking the sixth among all cancers in mortality.Despite advances in diagnosis and therapy,esophageal cancer still has a poor prognosis.Investigation of the immune escape mechanism can provide new insights for the treatment of esophageal can-cer.This article provides an overview of the mechanism of tumor immune escape as well as research progress in esophageal cancer.