Advances in exosomal microRNA and pathogenesis of preeclampsia / 中华围产医学杂志
Chinese Journal of Perinatal Medicine
;
(12): 622-625, 2018.
Artículo
en Chino
| WPRIM
| ID: wpr-711226
ABSTRACT
Preeclampsia is an idiopathic gestational disease with unknown etiology or pathogenesis. Exosomes are membranous nanovesicles secreted by various cells, carrying contents such as proteins, mRNA, microRNA and lipids and being involved in regulations between cells by transporting the above contents through target cells. The expression of exosome-derived proteins and microRNAs in preeclampsia patients experiences changes, resulting in maternal inadequate trophoblast invasion, depressed endothelial cell function and angiogenesis. Research on placenta-derived exosomal microRNAs in preeclampsia patients may help to elucidate the pathogenesis of preeclampsia.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Tipo de estudio:
Estudio de etiología
Idioma:
Chino
Revista:
Chinese Journal of Perinatal Medicine
Año:
2018
Tipo del documento:
Artículo
Similares
MEDLINE
...
LILACS
LIS