The effects of adrenergic and adrenergic blocking agents on the phosphorylase activity of bovine extraocular muscles
Journal of the Korean Ophthalmological Society
; : 11-16, 1972.
Article
en Ko
| WPRIM
| ID: wpr-71124
Biblioteca responsable:
WPRO
ABSTRACT
The author investigated the effect of adrenergic and adrenergic blocking agents on the phosphorylase activity of bovine extraocular muscle in vitro and obtained the following results: 1. The phosphorylase a activity of bovine extraocular muscle was revealed 53.6% in vitro. 2. The phosphorylase a activity of bovine extraocular muscle was slightly enhanced by the adrenergic agents such as epinephrine, norepinephrine and isoproterenol. 3. The phosphorylase a activity of bovine extraocular muscle was not affected by the adrenergic areceptor blocking agent, phenoxybenzamine but slightly inhibited by the adrenergic beta-receptor blocking agent, propranolol. 4. The phosphorylase a activity of bovine extraocular muscle previously treated with the adrenergic agents was blocked by a sole administration of propranolol or combined administrations of propranolol and phenoxybenzamine but not blocked by phenoxybenzamine alene.
Texto completo:
1
Índice:
WPRIM
Asunto principal:
Fenoxibenzamina
/
Fosforilasa a
/
Propranolol
/
Epinefrina
/
Norepinefrina
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Antagonistas Adrenérgicos
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Adrenérgicos
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Isoproterenol
/
Músculos
Idioma:
Ko
Revista:
Journal of the Korean Ophthalmological Society
Año:
1972
Tipo del documento:
Article