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Advances in pertussis toxin detoxification / 中华微生物学和免疫学杂志
Chinese Journal of Microbiology and Immunology ; (12): 796-800, 2018.
Artículo en Chino | WPRIM | ID: wpr-711456
ABSTRACT
Pertussis toxin (PT) is one of the major virulence factors of Borrelia pertussis and also an essential component of pertussis vaccines. Before using it in vaccine production, detoxification is necessa-ry because of its biological activity. This paper summarized the structure and detoxification process of PT as well as the safety and immunogenicity of pertussis vaccines prepared with detoxified PT.

Texto completo: Disponible Índice: WPRIM (Pacífico Occidental) Idioma: Chino Revista: Chinese Journal of Microbiology and Immunology Año: 2018 Tipo del documento: Artículo

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Texto completo: Disponible Índice: WPRIM (Pacífico Occidental) Idioma: Chino Revista: Chinese Journal of Microbiology and Immunology Año: 2018 Tipo del documento: Artículo