POCT in diagnosis of infectious diseases—the state of art and future / 中华检验医学杂志

ABSTRACT

The pathogen diagnosis of infectious diseases plays a critical role in the rational application of antibiotics , the monitoring and management of disease epidemiology and the control of drug -resistant bacteria in hospitals and communities .The ideal method for rapid detection of infectious diseases should be sensitive, rapid, specific, stable, low-cost and easy to use.This article reviews the clinical application of POCT in infectious disease antigen detection , antibody detection , nucleic acid detection , etc. and focuses on the advantages and potential of microfluidic technology in pathogen multiplex nucleic acid detection and drug resistance detection .Choosing the right time , the right place , and the right on-site rapid diagnostic technology will provide a new strategy for the diagnosis and treatment of infectious diseases in the graded diagnosis and treatment mode .