Research progress and screening strategies for biomarkers from extracellular vesicles in human diseases / 中华检验医学杂志

ABSTRACT

Extracellular vesicles ( EVs ) are small vesicles released by cells , which contain biomarkers , such as proteins and nucleic acids , etc.The research and application of EVs biomarkers have become one of the research hotspots internationally because EVs can sensitively reflect the pathological changes of the body and EVs detection have the advantages of non-invasive, simple sampling and real-time monitoring, comparing with tissue biopsy.This article reviews the current research status and screening strategies of EVs biomarkers aiming to encourage researchers to accelerate the development of screening and detection technologies for EVs biomarkers and translation into clinical diagnosis and treatment .