Clinical analysis of 210 cases of borderline ovarian tumors / 肿瘤研究与临床

ABSTRACT

Objective To investigate the clinicopathological characteristics and risk factors for recurrence of epithelial borderline ovarian tumors (BOT). Methods The data of 210 BOT patients from January 2001 to December 2015 in Shanxi Provincial Cancer Hospital were retrospectively analyzed. Results The mean age of 210 BOT patients was(41±16)years old including 68.1 %(143/210)patients of stage IA,and 31.9 %(67/210)patients>stage IA.Twenty-three patients had recurrence and the recurrence rate was 11.3 % (23/204); Univariate analysis showed that there were statistically significant differences in relapse rate among BOT patients with regard to age (P =0.007), stage (P =0.009), microemulsion pattern (P =0.024) and operative mode(P= 0.025). Multivariate logistic regression analysis showed that micropapillary pattern (OR=0.153, 95 % CI 0.044-0.535), the age (≤40 years old) (OR= 0.245, 95 % CI 0.088-0.686) and high stage (OR=3.502, 95 % CI 1.360-9.020) were risk factors for recurrence in BOT patients. Conclusions BOT mainly occurs in young women of child-bearing age,who are at an early stage and have a good prognosis. The patients who belong to 40 years old or below, the staging >ⅠAand micropapillary pattern would be easy to recur.