Progress of pathogenesis and molecular targeted therapy of ovarian cancer / 肿瘤研究与临床

ABSTRACT

Ovarian neoplasm has various histological types, and its main treatment is cytoreductive surgery combined with auxiliary chemotherapy. However, it has a high recurrence rate and effective control of disease is far from satisfaction owing to drug resistance of cancer cells to chemotherapeutics. With the development of molecular biology, genetics and clinical medicine including molecular classification, accurate screening and large epidemiological investigation, the pathogenesis and molecular targeted therapy for ovarian cancer has become a hot topic. This paper reviews the pathogenesis and molecular target therapy of ovarian cancer to provide data for clinical diagnosis and treatment.