Sudden Deaths of Neonates Receiving Intravenous Infusion of Lipid Emulsion Contaminated with Citrobacter freundii
Journal of Korean Medical Science
;
: e97-2018.
Artículo
en Inglés
| WPRIM
| ID: wpr-713499
ABSTRACT
At an intensive care unit, four neonates died consecutively within 80 minutes. Citrobacter freundii was isolated from blood samples of the 4 patients. It was also cultured from the leftover SMOFlipid that had been infused intravenously into the patients. In this in vitro study, we evaluated the bacterial growth kinetics and change in size of fat globules in SMOFlipid contaminated with C. freundii. Following the growth of bacteria, pH of SMOFlipid decreased to < 6, and the number of fat globules larger than 5 µm increased. Pulmonary fat embolism is proposed as a possible cause of the sudden deaths as well as fulminant sepsis.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Bacterias
/
Técnicas In Vitro
/
Infusiones Intravenosas
/
Citrobacter
/
Cinética
/
Citrobacter freundii
/
Sepsis
/
Muerte Súbita
/
Embolia Grasa
/
Emulsiones Grasas Intravenosas
Límite:
Humanos
/
Recién Nacido
Idioma:
Inglés
Revista:
Journal of Korean Medical Science
Año:
2018
Tipo del documento:
Artículo
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