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Clinical Characteristics and Incidence of Perianal Diseases in Patients With Ulcerative Colitis
Annals of Coloproctology ; : 138-143, 2018.
Artículo en Inglés | WPRIM | ID: wpr-715083
ABSTRACT

PURPOSE:

While perianal disease (PAD) is a characteristic of patients with Crohn disease, it has been overlooked in patients with ulcerative colitis (UC). Thus, our study aimed to analyze the incidence and the clinical features of PAD in patients with UC.

METHODS:

We reviewed the data on 944 patients with an initial diagnosis of UC from October 2003 to October 2015. PAD was categorized as hemorrhoids, anal fissures, abscesses, and fistulae after anoscopic examination by experienced proctologists. Data on patients’ demographics, incidence and types of PAD, medications, surgical therapies, and clinical course were analyzed.

RESULTS:

The median follow-up period was 58 months (range, 12–142 months). Of the 944 UC patients, the cumulative incidence rates of PAD were 8.1% and 16.0% at 5 and 10 years, respectively. The incidence rates of bleeding hemorrhoids, anal fissures, abscesses, and fistulae at 10 years were 6.7%, 5.3%, 2.6%, and 3.4%, respectively. The cumulative incidence rates of perianal sepsis (abscess or fistula) were 2.2% and 4.5% at 5 and 10 years, respectively. In the multivariate analyses, male sex (risk ratio [RR], 4.6; 95% confidence interval [CI], 1.7–12.5) and extensive disease (RR, 4.2; 95% CI, 1.6–10.9) were significantly associated with the development of perianal sepsis.

CONCLUSION:

Although the clinical course of PAD in patients with UC is not serious, in clinical practice, PAD is not rare in such patients. Therefore, careful examination and appropriate management for PAD is needed if the quality of life for patients with UC is to be improved.
Asunto(s)

Texto completo: Disponible Índice: WPRIM (Pacífico Occidental) Asunto principal: Calidad de Vida / Úlcera / Colitis Ulcerosa / Enfermedad de Crohn / Demografía / Incidencia / Análisis Multivariante / Estudios de Seguimiento / Sepsis / Diagnóstico Tipo de estudio: Estudio diagnóstico / Estudio de incidencia / Estudio observacional / Estudio pronóstico Límite: Humanos / Masculino Idioma: Inglés Revista: Annals of Coloproctology Año: 2018 Tipo del documento: Artículo

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Texto completo: Disponible Índice: WPRIM (Pacífico Occidental) Asunto principal: Calidad de Vida / Úlcera / Colitis Ulcerosa / Enfermedad de Crohn / Demografía / Incidencia / Análisis Multivariante / Estudios de Seguimiento / Sepsis / Diagnóstico Tipo de estudio: Estudio diagnóstico / Estudio de incidencia / Estudio observacional / Estudio pronóstico Límite: Humanos / Masculino Idioma: Inglés Revista: Annals of Coloproctology Año: 2018 Tipo del documento: Artículo