A Rare Case of Hyponatremia Caused by Reset Osmostat in a Neonate with Cleft Lip, Cleft Palate, and Imperforate Anus
Neonatal Medicine
;
: 131-135, 2018.
Artículo
en Inglés
| WPRIM
| ID: wpr-716552
ABSTRACT
Hyponatremia is defined as a plasma sodium concentration of < 135 mEq/L. It is a common electrolyte imbalance in newborns. We report the case of a term neonate with cleft lip, cleft palate, imperforate anus, normal male karyotype, and chronic hyponatremia. On the 4th day of life, he showed hyponatremia (plasma sodium concentration 130 mEq/L) with low serum osmolality (275 mOsm/kg), high urine sodium (116.7 mEq/L), and high urine osmolality (412 mOsm/kg). His thyroid and adrenal functions were normal. Despite intravenous and oral sodium supplementation and hydrocortisone treatment, hyponatremia persisted. Brain magnetic resonance imaging showed normal results. He was diagnosed as having reset osmostat, a rare subtype of the syndrome of inappropriate secretion of antidiuretic hormone characterized by a subnormal threshold for antidiuretic hormone secretion, with hypotonic hyponatremia.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Ano Imperforado
/
Concentración Osmolar
/
Plasma
/
Sodio
/
Glándula Tiroides
/
Encéfalo
/
Hidrocortisona
/
Imagen por Resonancia Magnética
/
Labio Leporino
/
Fisura del Paladar
Límite:
Humanos
/
Masculino
/
Recién Nacido
Idioma:
Inglés
Revista:
Neonatal Medicine
Año:
2018
Tipo del documento:
Artículo
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