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Kidney transplantation using expanded criteria deceased donors with terminal acute kidney injury: a single center experience in Korea
Annals of Surgical Treatment and Research ; : 278-285, 2018.
Artículo en Inglés | WPRIM | ID: wpr-718337
ABSTRACT

PURPOSE:

We investigated the clinical outcomes of deceased donor kidney transplantation (KT) using kidneys with terminal acute kidney injury (AKI).

METHODS:

Between February 2000 and December 2013, we performed 202 deceased donor renal transplants from 159 brain dead donors. According to the expanded criteria donor (ECD) and AKI network criteria, we divided 202 recipients into 4 groups Group I Non-AKI & standard criteria donor (SCD) (n = 97); group II Non-AKI & ECD (n = 15); group III AKI & SCD (n = 52); and group IV AKI & ECD (n = 38).

RESULTS:

The incidence of delayed graft function (DFG) was significantly higher in patients with AKI than it was in the non-AKI group (P = 0.008). There were no significant differences among the 4 groups in graft survival (P = 0.074) or patient survival (P = 0.090). However, the long-term allograft survival rate was significantly lower in group IV than it was in other groups (P = 0.024).

CONCLUSION:

Allografts from deceased donors with terminal AKI had a higher incidence of DGF than did those from donors without AKI. However, there is no significant difference in graft and patient survival rates among the groups. So, the utilization of renal grafts from ECDs with terminal AKI is a feasible approach to address the critical organ shortage.
Asunto(s)

Texto completo: Disponible Índice: WPRIM (Pacífico Occidental) Asunto principal: Donantes de Tejidos / Muerte Encefálica / Incidencia / Tasa de Supervivencia / Trasplante de Riñón / Trasplantes / Funcionamiento Retardado del Injerto / Lesión Renal Aguda / Aloinjertos / Supervivencia de Injerto Tipo de estudio: Estudio de incidencia / Estudio pronóstico Límite: Humanos País/Región como asunto: Asia Idioma: Inglés Revista: Annals of Surgical Treatment and Research Año: 2018 Tipo del documento: Artículo

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Texto completo: Disponible Índice: WPRIM (Pacífico Occidental) Asunto principal: Donantes de Tejidos / Muerte Encefálica / Incidencia / Tasa de Supervivencia / Trasplante de Riñón / Trasplantes / Funcionamiento Retardado del Injerto / Lesión Renal Aguda / Aloinjertos / Supervivencia de Injerto Tipo de estudio: Estudio de incidencia / Estudio pronóstico Límite: Humanos País/Región como asunto: Asia Idioma: Inglés Revista: Annals of Surgical Treatment and Research Año: 2018 Tipo del documento: Artículo