Developmental competence of in vitro-matured human oocytes obtained from pregnant and non-pregnant women / 대한생식의학회지
Clinical and Experimental Reproductive Medicine
;
: 189-194, 2018.
Artículo
en Inglés
| WPRIM
| ID: wpr-718516
ABSTRACT
OBJECTIVE:
The aim of this study was to compare the rate of maturation, fertilization, and embryo development of in vitro-matured human oocytes derived from pregnant and non-pregnant women.METHODS:
Immature oocytes were obtained by needle aspiration from 49 pregnant women (group 1) who underwent a cesarean section at term and 77 non-pregnant women (group 2) who underwent a gynecological operation during the same period (8 months). Healthy immature oocytes (530 in group 1 and 539 in group 2) were cultured and assessed for maturation 36 hours later. Mature oocytes were inseminated by intracytoplasmic sperm injection and cultured up to 144 hours.RESULTS:
The percentage of degenerated oocytes was significantly higher (12.1% vs. 6.3%; p < 0.001) in group 1 than in group 2. There was no significant difference in the maturation rate (66.8% vs. 68.1%; p=0.698), fertilization rate (66.7% vs. 67.6%; p=0.857), or the rate of formation of good-quality blastocysts (46.2% vs. 47.2%; p=0.898) in oocytes obtained from pregnant and non-pregnant women.CONCLUSION:
The developmental competence of immature oocytes did not differ between pregnant and non-pregnant women.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Oocitos
/
Blastocisto
/
Cesárea
/
Competencia Mental
/
Inyecciones de Esperma Intracitoplasmáticas
/
Mujeres Embarazadas
/
Desarrollo Embrionario
/
Fertilización
/
Técnicas de Maduración In Vitro de los Oocitos
/
Agujas
Límite:
Femenino
/
Humanos
/
Embarazo
Idioma:
Inglés
Revista:
Clinical and Experimental Reproductive Medicine
Año:
2018
Tipo del documento:
Artículo
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