A Case of Acute Panmyelosis with Myelofibrosis / 대한진단검사의학회지
The Korean Journal of Laboratory Medicine
;
: 207-211, 2004.
Artículo
en Coreano
| WPRIM
| ID: wpr-71945
ABSTRACT
We experienced a case of acute panmyelosis with myelofibrosis, one of the acute myeloblastic leukemia (AML) subtypes according to WHO classification. A 44 year old man presented with a laborious dyspnea, dizziness, and generalized weakness. On admission, the peripheral blood revealed pancytopenia (hemoglobin 4.0 g/dL, WBC 2, 300/microliter, platelet 92, 000/microliter) with leukoerythroblastosis. The bone marrow (BM) aspirate yielded inadequate material but histological sections showed hyper-cellularity, proliferation of trilineage cell lines (panmyelosis) with extensive myelofibrosis, and clusters of immature cells at paratrabecular area. On ultrasonographic examination, no evidence of hepato-splenomegaly or any other abnormalities were noted. The follow-up BM study after the chemotherapy with Ara C for 7 days and idarubicin for 3 days showed no significant changes in pancytopenia and myelofibrosis but revealed a significant decrease in BM cellularity and blasts. We review and report the literature on acute panmyelosis with myelofibrosis.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Pancitopenia
/
Plaquetas
/
Médula Ósea
/
Idarrubicina
/
Leucemia Mieloide Aguda
/
Línea Celular
/
Estudios de Seguimiento
/
Clasificación
/
Mareo
/
Quimioterapia
Tipo de estudio:
Estudio observacional
/
Estudio pronóstico
Idioma:
Coreano
Revista:
The Korean Journal of Laboratory Medicine
Año:
2004
Tipo del documento:
Artículo
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