Primary cutaneous B-cell lymphoblastic lymphoma in an elderly man
Korean Journal of Hematology
;
: 283-286, 2011.
Artículo
en Inglés
| WPRIM
| ID: wpr-720151
ABSTRACT
Precursor B-cell lymphoblastic lymphoma (B-LBL) is an uncommon high-grade neoplasm of immature B cells. It occurs predominantly in childhood with extranodal involvement such as skin and bone. Therefore, primary cutaneous involvement in elderly adults is a very rare manifestation of B-LBL. Here, we report a 78-year-old man with B-LBL presenting as a single cutaneous lesion which was immunohistochemically positive for leukocyte common antigen (LCA), CD79a, paired box 5 (PAX5), B cell lymphoma-2 (bcl-2), and terminal deoxynucleotidyl transferase (TdT) staining, but was without systemic involvement. The patient was treated using cyclophosphamide, adriamycin, vincristine, and prednisolone (CHOP), and achieved complete response (CR) at the first response assessment conducted after 3 CHOP cycles. After an additional cycle of CHOP treatment, radiotherapy was administered at a total dose of 3,600 cGy over 4 weeks. At the 21-month follow-up, he had maintained CR.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Piel
/
Vincristina
/
Prednisolona
/
Linfocitos B
/
Leucemia-Linfoma Linfoblástico de Células Precursoras B
/
Doxorrubicina
/
Estudios de Seguimiento
/
Antígenos Comunes de Leucocito
/
Ciclofosfamida
/
ADN Nucleotidilexotransferasa
Tipo de estudio:
Estudio observacional
/
Estudio pronóstico
Límite:
Adulto
/
Anciano
/
Humanos
Idioma:
Inglés
Revista:
Korean Journal of Hematology
Año:
2011
Tipo del documento:
Artículo
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