Metachronous Mantle Cell Lymphoma with Leukemic Presentation in a Patient with Early Gastric Cancer: A Case Report
Korean Journal of Hematology
;
: 247-252, 2008.
Artículo
en Inglés
| WPRIM
| ID: wpr-720503
ABSTRACT
We report here on a case of metachronous second primary non-Hodgkin's lymphoma (NHL) that was diagnosed 6 years after performing subtotal gastrectomy for treating early gastric cancer (EGC). The subtype analysis revealed mantle cell lymphoma (MCL) of the blastic variant with a leukemic presentation, which was composed of mixed small and medium-sized cells. The immunohistochemical staining for cyclin-D1 was positive. The cytogenetic study revealed t(4;6). In Korea, the risk of developing a second primary cancer following gastric cancer was reported to be less than 3.4%, and NHL comprised less than 6.3% of this second primary cancer. Furthermore, MCL represents about 2% of all lymphomas in Korea. To the best of our knowledge, this is the first report of metachronous primary MCL with a leukemic presentation following curative resection of EGC.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Neoplasias Gástricas
/
Linfoma no Hodgkin
/
Leucemia
/
Neoplasias Primarias Secundarias
/
Linfoma de Células del Manto
/
Citogenética
/
Gastrectomía
/
Corea (Geográfico)
/
Linfoma
Límite:
Humanos
País/Región como asunto:
Asia
Idioma:
Inglés
Revista:
Korean Journal of Hematology
Año:
2008
Tipo del documento:
Artículo
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