A Case of Chronic Neutrophilic Leukemia with Multiple Myeloma and an Increased Function of Her Neutrophils
Korean Journal of Hematology
;
: 151-156, 2007.
Artículo
en Inglés
| WPRIM
| ID: wpr-720801
ABSTRACT
We describe here a 64-year-old woman who simultaneously presented with chronic neutrophilic leukemia (CNL) and multiple myeloma (MM). The patient presented with mature neutrophilic leukocytosis, hepatosplenomegaly, the absence of Philadelphia chromosome and the BCR-ABL fusion gene, along with IgG kappa type monoclonal gammopathy in her serum and urine. The bone marrow aspirates showed hypercellularity with marked granulocytic hyperplasia and an increase in immature plasma cells. The neutrophil function tests showed increased phagocytosis, chemotaxis and respiratory burst activity, but there was normal microbial killing activity. The patient was treated with dexamethasone and pamidronate for MM and with hydroxyurea for CNL, and she was discharged from the hospital in an improved condition.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Paraproteinemias
/
Fagocitosis
/
Células Plasmáticas
/
Médula Ósea
/
Cromosoma Filadelfia
/
Inmunoglobulina G
/
Dexametasona
/
Leucemia Neutrofílica Crónica
/
Quimiotaxis
/
Estallido Respiratorio
Límite:
Femenino
/
Humanos
Idioma:
Inglés
Revista:
Korean Journal of Hematology
Año:
2007
Tipo del documento:
Artículo
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