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A Case Report of Posttransplant Lymphoproliferative Disorders Successfully Treated with R-CHOP in Korea
Korean Journal of Hematology ; : 106-112, 2008.
Artículo en Coreano | WPRIM | ID: wpr-720804
ABSTRACT
Posttransplant lymphoproliferative disorder (PTLD) is a group of heterogeneous lymphoid diseases that cause serious complications after organ or stem cell transplantation. The onset of PTLD is mostly due to EBV infection-induced B-cell proliferation and a defect in cytotoxic T cell function that occurs with immunosuppression. The usual treatment strategy for PTLD is reduction or withdrawal of immunosuppressive drugs with or without the administration of antiviral agents. Recently, various studies on the efficacy of rituximab or chemotherapy have been reported. We report two cases of rapidly progressing and complicated PTLDs after kidney transplantation that were successfully treated with a combination regimen consisting of rituximab, cyclophosphamide, adriamycin, vincristine and prednisolone (R-CHOP).
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Texto completo: Disponible Índice: WPRIM (Pacífico Occidental) Asunto principal: Antivirales / Vincristina / Prednisolona / Linfocitos B / Doxorrubicina / Terapia de Inmunosupresión / Trasplante de Riñón / Herpesvirus Humano 4 / Ciclofosfamida / Trasplante de Células Madre País/Región como asunto: Asia Idioma: Coreano Revista: Korean Journal of Hematology Año: 2008 Tipo del documento: Artículo

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Texto completo: Disponible Índice: WPRIM (Pacífico Occidental) Asunto principal: Antivirales / Vincristina / Prednisolona / Linfocitos B / Doxorrubicina / Terapia de Inmunosupresión / Trasplante de Riñón / Herpesvirus Humano 4 / Ciclofosfamida / Trasplante de Células Madre País/Región como asunto: Asia Idioma: Coreano Revista: Korean Journal of Hematology Año: 2008 Tipo del documento: Artículo