Primary Isolated Bone Marrow Diffuse Large B-cell Lymphoma with Hemolytic Anemia as the First Manifestation
Korean Journal of Hematology
;
: 48-52, 2008.
Artículo
en Inglés
| WPRIM
| ID: wpr-720813
ABSTRACT
Primary isolated bone marrow disease as a presenting feature of diffuse large B-cell lymphoma is very rare. We describe the first Korean case of isolated bone marrow diffuse large B-cell lymphoma with hemolytic anemia as the first manifestation. A32-year-old man was admitted to our hospital presenting with fever and hematuria. He had severe anemia and high lactate dehydrogenase activity. His peripheral blood smear and laboratory findings were suggestive of intravascular hemolytic anemia. The bone marrow biopsy revealed involvement with diffuse large B-cell lymphoma. A computed tomographic scan showed splenomegaly, but no lymphadenopathy. Our case shared some clinical features with the Asian variant of intravascular B-cell lymphoma, but there was infrequent involvement of the sinusoids of lymphoma cells and no hemophagocytosis. Our patient was treated with R-CHOP regimen for six cycles and he is in remission after autologous peripheral blood stem cell transplantation.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Esplenomegalia
/
Biopsia
/
Médula Ósea
/
Enfermedades de la Médula Ósea
/
Linfocitos B
/
Linfoma de Células B
/
Trasplante de Células Madre de Sangre Periférica
/
Pueblo Asiatico
/
Fiebre
/
Hematuria
Límite:
Humanos
Idioma:
Inglés
Revista:
Korean Journal of Hematology
Año:
2008
Tipo del documento:
Artículo
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